Multiple Sclerosis Impact Scale

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What It Measures

The Multiple Sclerosis Impact Scale (MSIS-29) is a self-report questionnaire that asks how much MS has affected a persons day-to-day life over the past two weeks. Twenty of the 29 questions cover the physical impact of the disease and nine cover the psychological impact, each answered on a five-point scale running from "not at all" to "extremely."

The two scales are scored separately and converted to a 0–100 range, where a higher score means greater impact. The developers do not recommend combining them into one number. Rehabilitation teams use it in outpatient, inpatient, home health, and skilled nursing settings to track change over a course of care.

Further Reading

Additional Notes

Licensing Notes: The MSIS-29 is copyrighted and permission must be obtained before use. Copyright is held by the Neurological Outcome Measures Unit (National Hospital for Neurology and Neurosurgery, Queen Square, London); the scale also carries a 2006 notice for the University of Plymouth, University College London, and Plymouth Hospitals NHS Trust. Neither source posts a fee schedule, so cost should be confirmed directly with the copyright holder.

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